Publicacions
El coneixement generat a IrsiCaixa es comparteix amb la comunitat científica a través de la publicació d’articles a revistes científiques d’alt impacte.
Restriction of HIV-1 replication in primary macrophages by IL-12 and IL-18 through the upregulation of SAMHD1.
Polymorphic LEDGF/p75 variants support efficient HIV-1 infection ex vivo.
Trans-infection but not infection from within endosomal compartments after cell-to-cell HIV-1 transfer to CD4+ T cells.
Antiretroviral agents effectively block HIV replication after cell-to-cell transfer.
Differential prevalence of the HLA-C -- 35 CC genotype among viremic long term non-progressor and elite controller HIV+ individuals.
Rare LEDGF/p75 genetic variants in white long-term nonprogressor HIV+ individuals.
Compensatory mutations rescue the virus replicative capacity of VIRIP-resistant HIV-1.
β5 integrin is the major contributor to the αVintegrin-mediated blockade of HIV-1 replication.
Development of resistance to VIR-353 with cross-resistance to the natural HIV-1 entry virus inhibitory peptide (VIRIP).
Different selection patterns of resistance and cross-resistance to HIV-1 agents targeting CCR5.