Our goal is to advance in the development of more effective and personalized treatments for microbial-based human diseases, through a better understanding of the biological determinants of health and disease at the population level. To achieve this goal, we focus our research on three main areas of interest:
1. Understanding the role of the gut microbiome in human health and disease. We use next-generation sequencing to characterize the distribution and function of the human gut microbiota in different conditions of health and disease. We are currently working on:
2. Improving genotypic viral diagnostic tools to maximize antiretroviral efficacy. We pioneered the introduction of next-generation sequencing of HIV-1 in Europe, leading a number of seminal studies to evaluate the clinical value of ultrasensitive tests of HIV-1 resistance and tropism in response to antiretroviral treatment. We work in close collaboration with diagnostic companies and academic centres in Europe, the USA and several African countries.
3. Defining the global clinical epidemiology of HIV-1. We work with leading European clinical cohorts (EuroCOORD, ESAR and EuroSIDA) and with African and American research groups in order to understand how the virus responds to treatment and affects clinical progression to AIDS and death.
Roger Paredes obtained a degree and doctorate in Medicine and Surgery from the Autonomous University of Barcelona (UAB). His specialism in HIV resistance, at Brigham & Women's Hospital in Boston and Harvard Medical School, was funded by a post-doctoral scholarship from “la...
Curriculum
Associate researcher
Marc Noguera i Julian
mnoguera@irsicaixa.es
Post-doctoral researcher
Maria Casadellà
mcasadella@irsicaixa.es
Laboratory technician
Mariona Parera
mparera@irsicaixa.es
Principal Investigator
Roger Paredes
rparedes@irsicaixa.es
Post-doctoral researcher
Aleix Elizalde Torrent
aelizalde@irsicaixa.es
Post-doctoral researcher
Alessandra Borgognone
aborgognone@irsicaixa.es
Post-doctoral researcher
Francesc Català Moll
fcatala@irsicaixa.es
Pre-doctoral researcher
Carlos Blázquez Bondia
cblazquez@irsicaixa.es
