Ageing is responsible for physiological dysfunctions in the different tissues, organs, and systems that leads to a decline in immune efficacy, resulting in increased vulnerability to infectious diseases, diminished responses to vaccination, and a major susceptibility to age-related inflammatory diseases.
Our group focuses on translational studies to investigate the remodelling of the immune system during the process of ageing in the context of infectious diseases. Thus, our group focuses on two main lines of research:
By working in close collaboration with the Infectious Disease unit of the Germans Trias i Pujol University Hospital, the ultimate goal is to better understand age-associated immune dysregulation and immunosenescence, in order to identify novel strategies for immune rejuvenation, effective vaccination response and successful treatments in the older individuals.
Marta Massanella graduated in Biology at the University Pompeu Fabra (Barcelona) and completed her PhD in Biomedicine at IrsiCaixa under the supervision of Dr. Julià Blanco in 2012. During her PhD, she characterized the immunodiscordant response to ART in HIV-treated individuals...
Curriculum