Roger Badia Córcoles
Roger Badia is a Miguel Servet I associate researcher (Instituto de Salud Carlos III, Ministry of Science, Innovation and Universities). He holds a PhD in Immunology from the Institute of Biotechnology and Biomedicine at the Autonomous University of Barcelona (IBB-UAB). His research focuses on the molecular mechanisms underlying host-pathogen interaction. Genome editing using CRISPR-Cas9 is the day-to-day toolbox he uses to study cellular cofactors and restriction factors implicated in the HIV replication cycle. Outside the lab he enjoys playing with his daughters, having fun with the guitar, playing rugby and being with his friends.
Pharmacological Inhibition of IKK to Tackle Latency and Hyperinflammation in Chronic HIV-1 Infection.
IRF7 expression correlates with HIV latency reversal upon specific blockade of immune activation.
New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains.
The cortical actin determines different susceptibility of naïve and memory CD4+ T cells to HIV-1 cell-to-cell transmission and infection.
SAMHD1 is active in cycling cells permissive to HIV-1 infection.