The sequencing service sequences reverse transcriptase, protease and/or integrase genes to detect mutations that imply genotypic HIV resistance to antiretroviral drugs. It also performs the HIV genotypic tropism test, which determines the cellular receptor used by HIV to enter cells, with resistance determined from plasma. For low virus loads in blood, samples are ultracentrifuged to obtain evaluable results from patient plasma.
The Sequencing Service, launched in 1999, has been a designated reference centre for antiretroviral resistance testing by the Catalan Health Service (CatSalut) since 2002. It also participates in research projects and clinical trials with other institutions and pharmaceutical companies.
This service is part of the CERCA GINYS platform, funded by CERCA with the support of the Spanish Ministry of Science and Innovation.
Head: Teresa Puig