The Sample Processing and Storage Service, in operation since 1993, supports scientific research in the biomedical field by processing and storing samples for use in both basic and clinical research.

Its biosafety level 3 (BSL-3) laboratory is equipped to ensure proper processing, transformation and storage of a wide variety of biological samples. The facilities also include various cryobiology rooms equipped with ultra-low freezers (-80ºC) and tanks of liquid nitrogen (-196ºC), permanently monitored through computerized recording and remote alarm systems.

The team has over 15 years experience in the isolation and storage of PBMCs, plasma, serum, urine, faeces, semen, vaginal fluid, biopsy material, etc. Some 350 samples are processed monthly.

The service has its own SOPs but adapts to the sample processing and storage protocols of sponsors for multicentre studies and to particular quality control and variable recording requirements.

Head: Eulàlia Grau - Contact

Tests include genotypic antiretroviral resistance determination in reverse transcriptase, protease and integrase as well as genotypic HIV tropism testing. Resistance is usually determined from plasma, but can also be determined from PBMCs or low-viral- load plasma (ultracentrifugation) for patient with low viral loads or with non-evaluable results.

The service, launched in 1999, was designated a reference centre for antiretroviral resistance testing by the Catalan Health Service in 2002. It also participates in research projects and clinical trials with other institutions and pharmaceutical companies.

Head: Teresa Puig - Contact