Pathogen Immunity, Signalling and Therapeutic Applications (PISTA)


Principal Investigator: Nuria Izquierdo-Useros


The world is becoming particularly vulnerable to emerging pathogens that thrive in new geographical areas due to globalization and climate change trends. Although infectious diseases can be contained by host defences, pathogens evolve to overcome immunity. The goal of this new group is to understand the underlying biology and features of human infection so as to develop novel therapeutic strategies against upcoming threats. As an emerging group studying emerging viruses, we aim to steer the rational design of broad antiviral treatments. Our research is framed within the IrsiCaixa strategic line of immunopathogenesis and other diseases. In our studies of emerging viruses and in our endeavour to develop innovative antiviral strategies and novel solutions to counteract microbial threats, our group collaborates with academic partners, different industries and clinical researchers based mainly at the Germans Trias i Pujol University Hospital.


Keywords: Emerging pathogens, immune responses, host susceptibility, HIV-1 co-infections, host-directed therapies, personalized treatments
Principal Investigator

Nuria Izquierdo-Useros

Nuria Izquierdo-Useros is a biologist from Madrid who obtained her PhD from the Autonomous University of Barcelona (UAB) in 2009. Her research focuses on the interplay between antigen presenting cells and enveloped viruses, and includes studies of the...


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Irsi Caixa

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'La Caixa' Foundation Generalitat de Catalunya - Departament de Salut


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