Publications
Knowledge generated at IrsiCaixa is shared with the scientific community through the publication of articles in high impact scientific journals.
On the steps of cell-to-cell HIV transmission between CD4 T cells.
Secretion of interferon-gamma by human macrophages demonstrated at the single-cell level after costimulation with interleukin (IL)-12 plus IL-18.
Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivo.
A dynamic target-based pharmacophoric model mapping the CD4 binding site on HIV-1 gp120 to identify new inhibitors of gp120-CD4 protein-protein interactions.
Transmission of drug-resistant HIV-1 is stabilizing in Europe.
Contribution of immunological and virological factors to extremely severe primary HIV type 1 infection.
Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis.
Rate of accumulation of thymidine analogue mutations in patients continuing to receive virologically failing regimens containing zidovudine or stavudine: implications for antiretroviral therapy programs in resource-limited settings.
Rare HLA drive additional HIV evolution compared to more frequent alleles.
Variability in the plasma concentration of efavirenz and nevirapine is associated with genotypic resistance after treatment interruption.