Publications
Knowledge generated at IrsiCaixa is shared with the scientific community through the publication of articles in high impact scientific journals.
Nucleotide embargo by SAMHD1: a strategy to block retroviral infection.
The cortical actin determines different susceptibility of naïve and memory CD4+ T cells to HIV-1 cell-to-cell transmission and infection.
Restriction of HIV-1 replication in primary macrophages by IL-12 and IL-18 through the upregulation of SAMHD1.
Polymorphic LEDGF/p75 variants support efficient HIV-1 infection ex vivo.
Computational studies identifying entry inhibitor scaffolds targeting the Phe43 cavity of HIV-1 gp120.
Insights from host genomics into HIV infection and disease: Identification of host targets for drug development.
Differential prevalence of the HLA-C -- 35 CC genotype among viremic long term non-progressor and elite controller HIV+ individuals.
Rare LEDGF/p75 genetic variants in white long-term nonprogressor HIV+ individuals.
Trans-infection but not infection from within endosomal compartments after cell-to-cell HIV-1 transfer to CD4+ T cells.
Antiretroviral agents effectively block HIV replication after cell-to-cell transfer.