Treatment of Chronic Mucocutaneous Candidiasis, an Unsolved Issue. Case Report and Literature Review

Treatment of Chronic Mucocutaneous Candidiasis, an Unsolved Issue. Case Report and Literature Review

Data de publicació online: 17/04/2017 Revista: Journal of Clinical & Cellular Immunology

Abstract:

Chronic mucocutaneous candidiasis (CMC) is a rare and heterogeneous group of disorders that may appear as an isolated disease or as a part of a complex syndrome (hyper-IgE syndrome or autoimmune polyendocrine syndrome-1 with ectodermal dystrophy). CMC can be transmitted as an autosomal-recessive (AR) or autosomal-dominant (AD) form, with common features including recurrent or persistent noninvasive Candida infections of the skin, nails, oral and genital mucosae, and associated autoimmune manifestations (most commonly endocrinopathies). It is caused by genetic faults in the immune system, through quantitative or qualitative, acquired or inherited T-cell deficiencies [1-4].

Autors: Tamara Caínzos-Romero, Sabela Sánchez-Trigo, Silvia Marfil-Verchili, Julià Blanco-Arbués, Hortensia Álvarez, Ana Mariño, Pascual Sesma-Sánchez and Josep M Llibre

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