Detection of a Sexually Transmitted Hepatitis C Virus Protease Inhibitor-Resistance Variant in a Human Immunodeficiency Virus–Infected Homosexual Man

Detection of a Sexually Transmitted Hepatitis C Virus Protease Inhibitor-Resistance Variant in a Human Immunodeficiency Virus–Infected Homosexual Man

Fecha de publicación online: 21/05/2014 Fecha de publicación en papel: 1 Septiembre 2014 Revista: Gastroenterology

Abstract:

There is an international epidemic of hepatitis C virus (HCV) infection among human immunodeficiency virus–infected men who have sex with men. Transmission of HCV variants that are resistant to recently approved direct-acting antivirals (DAAs) could be an important clinical and public health problem. We document a case of transmission of a DAA-resistant variant of HCV from a patient who was treated with telaprevir to his sexual partner. The transmission of HCV DAA-resistant variants could impair therapeutic regimens that include DAAs.

Autores: Franco S, Moltó J, Nevot M, Clotet B, Rockstroh J, Tural C, Martinez MA.

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Irsi Caixa

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'La Caixa' Generalitat de Catalunya - Departament de Salut

 

HR Excellence in Research

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