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IrsiCaixa >> Research >> Research groups >> Viral Entry and Pathogenesis

Viral Entry and Pathogenesis

Viral Entry and Pathogenesis

Publications

  • New nitrogen containing substituents at the indole-2-carboxamide yield high potent and broad spectrum indolylarylsulfone HIV-1 non-nucleoside reverse transcriptase inhibitors

    Giuseppe La Regina †, Antonio Coluccia †, Andrea Brancale ‡, Francesco Piscitelli †, Valeria Famiglini †, Sandro Cosconati II, Giovanni Maga #, Alberta Samuele #, Emmanuel Gonzalez ¥, Bonaventura Clotet ¥, Dominique Schols^, José A. Esté ¥, Ettore Novellino §, and Romano Silvestri †

    † Istituto Pasteur - Fondazione Cenci Bolognetti, Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma, Piazzale Aldo Moro 5, I-00185 Roma, Italy ‡ Welsh School of Pharmacy, Cardiff University, King Edward VII Avenue, Cardiff, CF10 3NB, U.K., Istituto di Chimica Biomolecolare, CNR, Piazzale Aldo Moro 5, I-00185 Roma, Italy # Institute of Molecular Genetics IGM-CNR, National Research Council, via Abbiategrasso 207, I-27100 Pavia, Italy ¥ IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, 08916 Badalona, Spain ^ Rega Institute for Medical Research, Katholieke Universiteit Leuven, B-3000 Leuven, Belgium § Dipartimento di Chimica Farmaceutica e Tossicologica, Università di Napoli Federico II, Via Domenico Montesano 49, I-80131, Napoli, Italy
    II Dipartimento di Scienze Ambientali, Seconda Università di Napoli, Via Vivaldi 43, 81100 Caserta, Italy

    J Med Chem. 2012 Jul 26;55(14):6634-8. doi: 10.1021/jm300477h. Epub 2012 Jul 6

  • HLA class I protective alleles in an HIV-1-infected subject homozygous for CCR5-Δ32/Δ32

    Ballana E, Riveira-Munoz E, Pou C, Bach V, Parera M, Noguera M, Santos JR, Badia R, Casadellà M, Clotet B, Paredes R, Martínez MA, Brander C, Esté JA.

    IrsiCaixa and AIDS Unit, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain

    Immunobiology(2012). DOI:10.1016/j.imbio.2012.06.012.

  • Antiretroviral agents effectively block HIV replication after cell to cell transfer

    Marc Permanyer, Ester Ballana, Alba Ruiz, Roger Badia, Eva Riveira-Munoz, Encarna Gonzalo, Bonaventura Clotet and José A. Esté
    IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain

    J Virol. June 2012, doi: 10.1128/​JVI.01044-12

  • Antiretroviral agents effectively block HIV replication after cell-to-cell transfer

    Marc Permanyer, Ester Ballana, Alba Ruiz, Roger Badia, Eva Riveira-Munoz, Encarna Gonzalo, Bonaventura Clotet and José A. Esté

     

    IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain

    J Virol. 2012 Aug;86(16):8773-80. doi: 10.1128/JVI.01044-12. Epub 2012 Jun 13

  • Diverse combinatorial design, synthesis and in vitro evaluation of new HEPT analogues as potential non-nucleoside HIV-1 reverse transcription inhibitors

    Puig-de-la-Bellacasa Ra, Giménez La, Pettersson Sa, Pascual Ra, Gonzalo Eb, Esté JAb, Clotet Bb, Borrell JIa, Teixidó J.a

     

    aGrup d'Enginyeria Molecular, Institut Químic de Sarrià, Universitat Ramon Llull bIrsiCaixa, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona

    Eur J Med Chem. 2012 Aug;54:159-74. doi: 10.1016/j.ejmech.2012.04.038. Epub 2012 May 4