Sharon Lewin, FRACP, PhD
Burnet Inst, The Alfred Hosp and Monash Univ, Melbourne, Australia
Combination ART (cART) has led to a major reduction in HIV-related mortality and morbidity, but HIV can still not be cured. The major barriers to cure include latently infected cells, low-level persistent virus replication, and anatomical reservoirs.
There is now emerging evidence that persistent immune activation and cell–cell transfer of virus may facilitate virus persistence in patients on cART, specifically in tissue such as the gastrointestinal tract. Achieving either a functional cure (long-term control of HIV in the absence of cART) or a sterilizing cure (elimination of all HIV+ cells) remains a major challenge.
The seminar will take place on Tuesday 5th June at 15.00h at:
University Hospital Germans Trias i Pujol
Conference hall (Sala d'Actes) - Free entrance
Carretera de Canyet, s/n